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Remember me on this computer. Obaidur Rahman! PARAGRAPH ! The effect of CsA on the uptake of [11C]verapamil in the brain was best described by an inhibitory indirect effect model with an effect on the transport of [11C]verapamil out of the brain. Related Papers. Click here to sign up. Piero Chiarelli. Vaccine Updated aluminum pharmacokinetics following infant exposures through diet and vaccination? CsA was administered as a bolus followed by a constant infusion 20 min after the start of the [11C]verapamil infusion.
This article describes the experimental more info and pharmacokinetic modeling of P-glycoprotein function in the rat blood-brain barrier using [11C]verapamil as the substrate and cyclosporin A as an inhibitor of P-gp.
